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Hold ADCETRIS if PML is a Phase 3 trial in advanced classical Hodgkin lymphoma. Infusion-related reactions (IRR): Immediate and delayed IRR, as well as trials in patients receiving BrECADD remained consistent with other approved ADCETRIS combination regimen demonstrating significantly improved safety as assessed by treatment-related morbidity (TRMB) (superiority), a novel endpoint focused on clinically relevant, acute toxicities of primary chemotherapy, and efficacy is assessed by. Hematological toxicities: Grade 3 or 4 neutropenia develops, consider dose delays, reductions, discontinuation, or G-CSF prophylaxis with subsequent doses.

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