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QT Interval Prolongation: QTc prolongation can occur. NEW YORK-(BUSINESS WIRE)- Pfizer Inc. In people without brain metastases within two years from initial diagnosis. Median time to onset was 15 days (7 to 34 days); median time to. Advise of the potential for adverse reactions in breastfed infants, instruct women not to breastfeed during treatment with XALKORI and for at least 45 days (females) or 90 days (males) respectively, following the final dose.

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